Juniper Publishers Gastroenterology Open Access Journals

  ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY JUNIPER PUBLISHERS Authored by Bhaswati C Acharyya Abstract Child hood immunization to prevent infectious diseases was one of the most successful health care steps in the last century. Presently allergy is increasing all over the world. Cow’s Milk Protein Allergy is the commonest food protein allergy in infancy, at the highest vaccine receiving age of life. Few children with CMPA showed Gastrointestinal symptoms like diarrhoea, vomiting and screaming episodes following Oral Polio Vaccination. This initiated the following retrospective observational study to see the present relation and pattern of reactions after polio vaccination in children with CMPA and whether this type of reactions can give a hint towards diagnosis of CMPA in undiagnosed or missed CMPA cases. Keywords:  Vaccination; Child hood; Immunization; Infectious diseases; Cow’s milk; Protein allergy Abbrevations:  GI: Gastro Intestinal; CMPA: Cow’s Milk ...

    ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY   JUNIPER PUBLISHERS Authored by Matthew Rolfsen Abstract Background:  Biologics, specifically anti-TNF agents, have been an integral part of our treatment paradigm for IBD for several years. However, therapeutic drug monitoring (TDM) enhances our ability to optimize dosing regimens. Studies have shown that trough levels<4.9ug/mL are associated with loss of response to adalimumab (ADA). An increased body weight may change the pharmacokinetics of adalimumab in IBD. The primary aim of this study was to evaluate the impact of body mass index (BMI) on adalimumab drug levels in IBD patients, as well as its potential clinical implications. Methods: A database was compiled via retrospective chart review of 507 IBD patients seen at our Digestive Disease Center (DDC) between July 2013 and March 2016. Variables in the database include patient’s weight, medications, serum adalimumab levels, dates of medication admini...

 

    ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY   JUNIPER PUBLISHERS   Authored by Elroy Patrick Weledji Abstract A fistula has a primary tract and may have secondary extensions. Complete eradication of both may lead to cure. Lay- open (fistulotomy) is the most certain treatment where it is possible and when the risks have been properly explained and accepted. Anterior fistulas in women are dangerous and should only rarely be laid open. The technique of fistulectomy, which excises rather than incises the fistula track, has been criticised on the basis of the greater tissue loss leading to delayed healing. However, fistulectomy by a core-out technique rather than excision of the track have several advocates. The paper discussed the natural history of the idiopathic anal fistula and the pros and cons of these two common modes of treatment. Keywords:  Fistulotomy; Fistula; Eradication; Idiopathic anal; Chronic anal fistula; Crohn’s disease Abbrevations:...