Juniper Publishers Gastroenterology Open Access Journals

    ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY   JUNIPER PUBLISHERS Authored by Guadalupe Abigail Benitez Lopez Abstract Gastrointestinal Carcinoid Tumors are neoplasms that originate in the lining of the gastrointestinal (GI) tract and are derived from the neuroendocrine cells. It is rare for these tumors to be detected before they develop metastases, and they are often discovered incidentally during surgery for other abdominal conditions. Currently, various treatment options are available for managing these tumors, such as surgery, which is usually the most effective treatment. The type of surgery depends on several factors, including the size and location of the tumor, the patient's comorbidities, and the presence of carcinoid syndrome. As a result of the low probability of metastasizing, surgery is typically the best treatment option for neuroendocrine tumors of type I. NETs of type II and III are the most aggressive and require a formal gastrostomy, where...

       ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY   JUNIPER PUBLISHERS Authored by Hjouj Mohammad Abstract Background : Hepatocellular carcinoma (HCC) is one of the most common cause of cancer-related deaths worldwide. The objective of this study is to detect the various stages of HCC through the utilization of a dynamic liver phantom with MRI. Methods:  Three liver phantoms composed of different gelatin concentrations (2.5%wt, 4.0%wt, and 5.0%wt) and fixed agar concentrations were used. The HCC samples consisted of agarose and glycerol and were of varying sizes (0.5,1.0, and 2.0cm). The chemical, mechanical, electrical, and imaging properties of the phantoms were examined. The consistency of T1 and T2 signal intensities over a six-week period was studied. In addition, dynamic contrast-enhanced MRI was used to detect the HCC samples through the Dixon sequence. Results:  The gelatin concentration of 5%wt was the most stable in regard to dens...

                                                      ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY   JUNIPER PUBLISHERS Authored by Annalisa Pasetti Abstract Vedolizumab (VDZ) is a monoclonal antibody that inhibits the interaction of α4β7 integrin with mucosal addressing cell adhesion molecule-1 (MAdCAM-1). Although it has been increasingly used to treat Crohn's disease (CD), its efficacy in preventing postoperative recurrence of CD is still unknown. Here we report a case of a patient with CD localized in the ileum with multiple stenosing lesions and fibrotic tracts. He was previously treated with anti-TNFα agents without disease control. Thus, he underwent laparoscopic ileocecal resection and three ileal strictureplasty surgeries. Ileo-colic resection was performed, and pathology confirmed the presence of a fibrotic stricture. Six months ...