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Showing posts from June, 2023

Impact of Surgery on Impacted Dentures in the GIT -Case Series and Review of Literature

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      ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY   JUNIPER PUBLISHERS  Authored by  Amarjothi JMV Abstract Dentures are an important cause of impaction in the Gastrointestinal tract especially in the elderly. These impacted dentures may be frequently overlooked due to their radiolucency and are frequently not amenable for endoscopic retrieval necessitating surgery for retrieval of these foreign bodies. The aim of this study is to describe the type of impaction, site, consequences and time interval to therapeutic intervention including the type of intervention and outcomes after accidental swallowing of dentures in a tertiary care referral hospital and assess the same in published medical literature throughout the world. From our experience, it is seen that dentures impacted in the cervical esophagus present earlier than those impacted in the thoracic esophagus as they are more symptomatic. Leaks at the primary closure site are more common in the...

Study the Effect of Weight Loss in Improvement of Hepatic Fibrosis in Patients with Chronic HCV

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    ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY   JUNIPER PUBLISHERS   Authored by Khaled Metwally Abstract Background:  Liver fibrosis considered as a reversible disease, but curing the primary hepatic disease, sometimes, doesn’t mean fibrosis improvement. Steatosis could be one of the reasons responsible for this failure. Weight loss has been shown to improve fibrosis, but few data is available from Egypt. Objective:  to test the effect of weight reduction on the degree of fibrosis improvement in patients with chronic hepatitis C (CHC). Methods: Adult patients (> 18 years) were recruited from hepatitis Cout patient’s clinic, National Liver Institute (NLI), University of Menoufyia, from 2016 to 2018. Results:  Thirty CHC patients with moderate and severe steatosis, who were initially assessed by liver biopsy and Transient elastography (TE) for their fibrosis stage, were followed up by Transient elastography after losing >10% of their ...

A Summary of the Main Biomarkers for Diagnosis and Prognosis of Sporadic Colorectal Cancer: A Review

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  ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY   JUNIPER PUBLISHERS Authored by Eny Maria Goloni-Bertollo Abstract Sporadic colorectal cancer (SCRC) affects regions of the large intestine (colon) and rectum that are not of family origin. The carcinogenesis process involves the interaction between environmental and genetic factors. This tumor is characterized by intestinal obstruction, bleeding (hematochezia, enterorrhagia), an altered bowel habit, and systemic conditions, such as weight loss. Some risk factors for SCRC are age over 60 years, a diet with high saturated fat, red meat, alcohol consumption, and smoking. An early diagnosis is essential for effective patient treatment and survival. Finding more effective and less invasive tumor, such as biomarkers, are important for ensuring that people participate in cancer screenings. Some studies have evaluated molecular biomarkers, such as micro ribonucleic acids (microRNAs, or miRNAs) and genes, in relation to the pat...