Juniper Publishers Gastroenterology Open Access Journals

Abstract Background and study aim: The bleeding from gastric varices are more severe, requiring more blood transfusions, and has a higher mortality rate than esophageal variceal bleeding, there is little data on primary prophylaxis of GV bleeding, we compared the efficacy of cyanoacrylate injection and beta-blockers in primary prophylaxis of gastric variceal bleeding. Methods: Cirrhotics with gastroesophageal varices type 2 with eradicated esophageal varices or large isolated gastric varix type 1, who had never bled from gastric varix, were randomized to cyanoacrylate injection (Group I, n = 30), beta-blockers (Group II, n = 30) or no treatment (Group III, n = 30). Primary endpoints were bleeding from gastric varix or death. Results: bleeding from gastric varices over 6 months follow up was 6.67% in Group I, 20% in Group II, 36.67% in Group III (p = 0.017). GV obliterated or decreased in size 42.86% and 57.14% of group I respectively. No patients neither in g...

Abstract Tailgut cysts are rare para-rectal lesions thought to arise from incomplete involution of the tailgut during ontogenesis. They commonly present to gastroenterologists with tenesmus, extra-luminal compression, disturbance of bowel habit or rectal bleeding and carry significant threat of malignant transformation; particularly adenocarcinoma. Guidelines on treatment of colonic adenocarcinoma are well established internationally. However, there are no guidelines on tailgut cyst management which can make onward referral for consideration of resection challenging. This problem is compounded by the inaccessibility of these cysts to visualisation or biopsy by endoscopy. A significant barrier to consensus on the approach to these lesions is that there is presently scant explanation on their morphogenesis. Ontogenesis is the guiding principle in resection of colonic adenocarcinoma, where the lesions are resected en bolc with their embryonic mesentery, which conta...

  Abstract Herbal and dietary supplements (HDS) encompass a large number of products with a wide range of ingredients. The use of HDS and the risk of hepatotoxicity is well documented; however, despite increasing awareness and many publicized cases, instances of new HDS-related injury continue to occur. Here, we highlight recent case reports, reviews, and research describing relatively new herbal and dietary supplement-induced liver injury. In particular, we focus on several of the more recently implicated products, such as kratom, weight loss supplements including multi-ingredient products (such as OxyELITE-Pro), Garcinia cambogia, CBD oil and energy drinks. Read More About This Article: https://juniperpublishers.com/argh/ARGH.MS.ID.555904.php Read More Juniper Publishers Google Scholar Articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=4DviEq0AAAAJ&citation_for_view=4DviEq0AAAAJ:u9iWguZQMMsC