ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY JUNIPER PUBLISHERS Authored by Myron R Szewczuk Abstract Gastrointestinal (GIJ cancer is an all-encompassing term that refers to the forms of cancers of the digestive system including the esophagus, liver, gallbladder, stomach, small intestine, colon, rectum, anus and pancreas. Of the cancers mentioned, pancreatic ductal adenocarcinoma (PDACJ is the most deadly form of GI cancer owing partially to the late detection of this malignancy. At this point of diagnosis, the disease has metastasized and very few treatment options are available to patients. The aggressive nature of this cancer can be attributed to the substantial number of mutations acquired during its progression and its subsequent resistance to standard therapies such as chemotherapy and radiationThe heterogeneity of the subpopulations that are chemoresistant, particularly the tumor initiating population as known as cancer stem cells...
Comments
Post a Comment