Juniper Publishers Gastroenterology Open Access Journals

  JUNIPER PUBLISHERS-Advanced Research in Gastroenterology & Hepatology     SERUM SEROTONIN AS A NOVEL MARKER FOR HEPATOCELLULAR CARCINOMA Authored by Elsayed Ibrahim Elshayeb Aim of the Work: To investigate the role of serum serotonin as a novel marker for diagnosis of Hepatocellular carcinoma In comparison with serum alpha fetoprotein. Introduction: Hepatocellular carcinoma is the most common liver cancer and is a disease with poor prognosis. In addition to its function as a neurotransmitter and vascular active molecule, Serotonin is also a mitogen for hepatocytes and promotes liver regeneration and may be involved in tumorigenesis of HCC. Methods: The study conducted on 136 patients and 20 healthy subjects as control group. Patients classified into two groups, 68 Cirrhotic with HCC as group I and 68 only cirrhotic without HCC as group II. Patients and controls underwent through history taking, full clinical examination with Child pugh...

  JUNIPER PUBLISHERS-Advanced Research in Gastroenterology & Hepatology Transient Elastography Is Superior To The Fib 4 Index, Aspartate Platelet Ratio Index, Aspartate Alanine Aminotransferase Ratio, Age Platelet Index And Fibrosis Index In Diagnosing Fibrosis In Chronic Hepatitis B Patients Authored by Raymond Kwok Introduction: Transient Elastography is a promising form of non-invasive assessment of fibrosis in chronic hepatitis B. The diagnostic accuracy and usefulness of TE is evaluated and compared with FIB 4 index, Aspartate Platelet Ratio Index (APRI), Aspartate Alanine aminotransferase Ratio (AAR), Age Platelet Index (API) and Fibrosis Index (FI). Methods: Chronic hepatitis B patients who had a liver biopsy within the past 6 months were identified and invited to have TE. Clinical history, laboratory data and pathology were collected TE was performed as per the manufacturer’s instructions. At least 10 successful measurements wer...