Irritable Bowel Syndrome is a Multisystemic Inflammatory Disorder
ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY JUNIPER PUBLISHERS Authored by Mehmet Rami Helvaci Abstract Background: irrtable bowel syndrome (IBS) is a common cause of recurrent complaints about gastrointestinal and genitourinary tracts in adults. Method: Consecutive patients with IBS and age and sex-matched controls were studied. IBS was diagnosed according to Rome II criteria in the absence of red flag symptoms including pain, diarrhea interfering with sleep, weight loss, fever, and any pathological finding with physical examination. Current daily smokers, patients with regular alcohol consumption (one drink a day), and patients with inflammatory, infectious, or devastating disorders were excluded. Results: The study included 291 patients with the IBS (245 females and 46 males) and 186 control cases (156 females and 30 males). Interestingly, mean age of the IBS patients was 42.9±13.9 (17-76) years, and 84.1% of them were female. Although the mean bo...