ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY JUNIPER PUBLISHERS Authored by Nishant Shukla Introduction Diarrhoeal disease with inflammation of colon or large intestine present with abdominal pain discomfort, passing of liquid stools with mucus, blood or bleeding were observed in ulcerative colitis, Crohn’s disease, etc. pathogenesis of large intestine was grouped as Inflammatory bowel disease. The disease was believed to be occurring due to indulgence of unwholesome food and routines. Mythological texts narrate that the diarrhoeal disease first occurred after demolition of Daksha Yagyna due to indulgence of beef, alcoholic beverages, other unwholesome food, routines and Shiva Kopa (stress induced). The disease has been narrated in ancient scientific texts i.e. Vedas. Ancient ayurvedic texts Charaka Samhita (1500 BC) and Acharya Sushruta (1200 BC) narrated the disease in Chikitsa Sthana (sections dealing with medical management of di...