ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY JUNIPER PUBLISHERS Authored by Qaiser Jabeen Abstract Coriander ( Coriandrum sativum L.) seeds have been documented for their traditional use in lowering cholesterol. The seeds were evaluated for their anticholelithic effects as no satisfactory pharmacological treatment is yet available for cholelithiasis, except cholelithotomy. Cholelithiasis was induced in albino mice by feeding them with high fat diet (HFD) for eight weeks. Treatment group was given 10 % coriander seeds powder (CsS) added in HFD. Experimental animals were analyzed for percent weight gain, total cholesterol levels and cholesterol gallstone grade. Histopathological analysis of gallbladder was also performed. CsS was found to be effective in reducing cholesterol gallstone incidence, preventing hypercholesterolemia and excessive weight gain in experimental animals. The data obtained from the current study justified t...
