Hebatitis B Virus Genotypes in Pakistan_Juniper Publishers
ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY JUNIPER PUBLISHERS Authored by Majid Mahmood Mini Review Hepatitis B virus (HBV) infection is one of the most common causes of human death worldwide [ 1 - 3 ]. HBV has ten genotypes alphabetized as A to J which are not uniformly distributed in different parts of the world. The genotypes are important in treatment of the infection as they influence the disease progression, baseline viral load and the patients' response to treatment. Distribution of HBV genotypes in the world According to Bonino et al. [ 2 ], who reviewed the global distribution of HBV genotypes, various HBV genotypes are not uniformly distributed all over the world. Further, their distribution is influenced by ethnic and geographical factors. Genotype A is common in Brazil, North America, Northwest Europe, South Asia, Central Africa, Tunisia and Benin [ 2 , 4 , 5 ]. Genotype B is common in China, Hong Kong, I...